{"id":35,"date":"2016-04-19T08:48:06","date_gmt":"2016-04-19T06:48:06","guid":{"rendered":"http:\/\/zoo.sav.sk\/en\/?page_id=35"},"modified":"2024-07-22T08:52:52","modified_gmt":"2024-07-22T06:52:52","slug":"apvv-projects","status":"publish","type":"page","link":"https:\/\/zoo.sav.sk\/en\/projects\/apvv-projects\/","title":{"rendered":"APVV Projects"},"content":{"rendered":"<h2>National<\/h2>\n<table class='project_list'>\n<tr>\n<td class='bold' colspan='2'>CLIMBER &#8211; Ekosyst\u00e9my vysokohorsk\u00fdch jazier v meniacom sa svete: klimatick\u00e1 zmena a obnova z acidifik\u00e1cie<\/td>\n<\/tr>\n<tr>\n<td class='bold' colspan='2'>High-altitude lake ecosystems in a changing world: climate change and recovery from acidification<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Program: <\/td>\n<td width='70%'>SRDA<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Project leader: <\/td>\n<td width='70%'>prof. Ing. Hamerl\u00edk Ladislav, PhD.<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Duration: <\/td>\n<td width='70%'>1.9.2025 &#8211; 31.8.2029<\/td>\n<\/tr>\n<\/table>\n<table class='project_list'>\n<tr>\n<td class='bold' colspan='2'>Cirkul\u00e1cia v\u00edrusu klie\u0161\u0165ovej encefalit\u00eddy v bl\u00edzkosti po\u013enohospod\u00e1rskych fariem a lesn\u00fdch lokalit\u00e1ch na Slovensku<\/td>\n<\/tr>\n<tr>\n<td class='bold' colspan='2'>Circulation of tick-borne encephalitis virus in foci close to agricultural farms and in sylvatic sites of Slovakia<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Program: <\/td>\n<td width='70%'>SRDA<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Project leader: <\/td>\n<td width='70%'>RNDr. Kazim\u00edrov\u00e1 M\u00e1ria, CSc.<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Duration: <\/td>\n<td width='70%'>1.7.2024 &#8211; 30.6.2028<\/td>\n<\/tr>\n<\/table>\n<table class='project_list'>\n<tr>\n<td class='bold' colspan='2'>Elimin\u00e1cia klie\u0161\u0165ami pren\u00e1\u0161an\u00fdch infekci\u00ed bez pou\u017eitia antibiot\u00edk<\/td>\n<\/tr>\n<tr>\n<td class='bold' colspan='2'>Non-antibiotic approach for the treatment of tick-borne infections<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Program: <\/td>\n<td width='70%'>SRDA<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Project leader: <\/td>\n<td width='70%'>Mgr. Selyemov\u00e1 Diana, PhD.<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Duration: <\/td>\n<td width='70%'>1.7.2024 &#8211; 30.6.2028<\/td>\n<\/tr>\n<\/table>\n<table class='project_list'>\n<tr>\n<td class='bold' colspan='2'>Od g\u00e9nov k metabolizmu: Identifik\u00e1cia a charakteriz\u00e1cia nov\u00fdch katabolick\u00fdch regul\u00e1torov v\u00ednnych mu\u0161iek<\/td>\n<\/tr>\n<tr>\n<td class='bold' colspan='2'>From genes to metabolism: Identification and characterization of novel catabolic regulators in the fruit fly model<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Program: <\/td>\n<td width='70%'>SRDA<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Project leader: <\/td>\n<td width='70%'>Mgr. G\u00e1likov\u00e1 Martina, PhD.<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Duration: <\/td>\n<td width='70%'>1.7.2024 &#8211; 30.6.2028<\/td>\n<\/tr>\n<\/table>\n<table class='project_list'>\n<tr>\n<td class='bold' colspan='2'>\u0160t\u00fadium \u00falohy mikroRNA v dlhodob\u00fdch \u00fa\u010dinkoch teploty po\u010das v\u00fdvinu na stresov\u00fa rezistenciu a d\u013a\u017eku \u017eivota<\/td>\n<\/tr>\n<tr>\n<td class='bold' colspan='2'>Unravelling the role of microRNAs in mediating the long-term effects of developmental temperature on stress tolerance and lifespan<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Program: <\/td>\n<td width='70%'>SRDA<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Project leader: <\/td>\n<td width='70%'>Mgr. et Mgr. Klepsatel Peter, PhD.<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Duration: <\/td>\n<td width='70%'>1.7.2024 &#8211; 30.6.2028<\/td>\n<\/tr>\n<\/table>\n<table class='project_list'>\n<tr>\n<td class='bold' colspan='2'>The analysis of neuropeptide-receptor signaling pathways in ticks<\/td>\n<\/tr>\n<tr>\n<td class='bold' colspan='2'>&#8211;<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Program: <\/td>\n<td width='70%'>SRDA<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Project leader: <\/td>\n<td width='70%'>RNDr. \u017dit\u0148an Du\u0161an, DrSc.<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Duration: <\/td>\n<td width='70%'>1.7.2024 &#8211; 30.6.2028<\/td>\n<\/tr>\n<\/table>\n<table class='project_list'>\n<tr>\n<td class='bold' colspan='2'>BioStimul &#8211; Experiment\u00e1lny syst\u00e9m pre bezkontaktn\u00fa stimul\u00e1ciu a monitorovanie vybran\u00fdch biologick\u00fdch vlastnost\u00ed a kognit\u00edvnych schopnost\u00ed Drosophila melanogaster<\/td>\n<\/tr>\n<tr>\n<td class='bold' colspan='2'>Experimental System for Wireless Stimulation and Monitoring of Selected Biological Properties and Cognitive Abilities of Drosophila melanogaster<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Program: <\/td>\n<td width='70%'>SRDA<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Project leader: <\/td>\n<td width='70%'>RNDr. Tak\u00e1\u010d Peter, CSc.<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Duration: <\/td>\n<td width='70%'>1.9.2024 &#8211; 30.6.2027<\/td>\n<\/tr>\n<\/table>\n<table class='project_list'>\n<tr>\n<td class='bold' colspan='2'>INFOTICK &#8211; Z\u00edskanie pravdiv\u00fdch inform\u00e1ci\u00ed o klie\u0161\u0165och<\/td>\n<\/tr>\n<tr>\n<td class='bold' colspan='2'>Getting the right info on ticks<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Program: <\/td>\n<td width='70%'>SRDA<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Project leader: <\/td>\n<td width='70%'>Mgr. Rus\u0148\u00e1kov\u00e1 Tarage\u013eov\u00e1 Veronika, PhD.<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Duration: <\/td>\n<td width='70%'>1.7.2023 &#8211; 30.6.2027<\/td>\n<\/tr>\n<\/table>\n<table class='project_list'>\n<tr>\n<td class='bold' colspan='2'>Expresia a funkcia calciton\u00ednu podobn\u00fdch peptidov a ich receptorov u klie\u0161\u0165ov<\/td>\n<\/tr>\n<tr>\n<td class='bold' colspan='2'>Expression and function of calcitonin-like peptides and their receptors in ticks<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Program: <\/td>\n<td width='70%'>SRDA<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Project leader: <\/td>\n<td width='70%'>Ing. Roller Ladislav, PhD.<\/td>\n<\/tr>\n<tr>\n<td width='30%' style='vertical-align: top;'>Annotation: <\/td>\n<td width='70%'>In this project we will focus on identification, expression and functional analysis of tick peptides related toevolutionarily conserved calcitonins. In insects and vertebrates, these peptides control essential physiologicalfunctions such as water and ion balance, metabolism, feeding behaviour and reproduction. We will use the ticksIxodes ricinus and I. scapularis as model species, as the role of neuropeptides in these vectors of dangerouspathogens is poorly understood. To elucidate signalling pathways of tick calcitonin-like peptides (CTs), we will usebioinformatics, cDNA cloning, qRT-PCR, in situ hybridisation and immunohistochemical staining with newly developed antibodies against tick CTs. Predicted receptors for CTs will be functionally characterised and theirspatial and temporal expression in tick organs determined by qRT-PCR. Electrophysiological techniques and microscopic video analysis will be used to determine effects of CTs on the salivary glands, digestive tract andreproductive organs in vitro. Changes in production and activity of digestive enzymes in intestinal extracts will beanalysed by Western blots. We will investigate peptide-receptor signalling pathways by suppressing expression of CTs receptors by RNA interference (RNAi). A very important part of this project is detailed analysis of effects of vaccination or CT receptor suppression by RNAi on transmission of pathogens Borrelia burgdorferi and B. afzelii. These modern and original approaches could reveal new mechanisms in tick blood feeding and reproduction, as well as very complex interactions between ticks, pathogens and hosts.<\/td>\n<\/tr>\n<tr>\n<td width='30%'>Duration: <\/td>\n<td width='70%'>1.7.2022 &#8211; 30.6.2026<\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>National CLIMBER &#8211; Ekosyst\u00e9my vysokohorsk\u00fdch jazier v meniacom sa svete: klimatick\u00e1 zmena a obnova z acidifik\u00e1cie High-altitude lake ecosystems in a changing world: climate change&#8230;<span class=\"excerpt_more\"><a href=\"https:\/\/zoo.sav.sk\/en\/projects\/apvv-projects\/\">\u010d\u00edta\u0165 \u010falej &raquo;<\/a><\/span><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":53,"menu_order":10,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_links_to":"","_links_to_target":""},"_links":{"self":[{"href":"https:\/\/zoo.sav.sk\/en\/wp-json\/wp\/v2\/pages\/35"}],"collection":[{"href":"https:\/\/zoo.sav.sk\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/zoo.sav.sk\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/zoo.sav.sk\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/zoo.sav.sk\/en\/wp-json\/wp\/v2\/comments?post=35"}],"version-history":[{"count":2,"href":"https:\/\/zoo.sav.sk\/en\/wp-json\/wp\/v2\/pages\/35\/revisions"}],"predecessor-version":[{"id":149,"href":"https:\/\/zoo.sav.sk\/en\/wp-json\/wp\/v2\/pages\/35\/revisions\/149"}],"up":[{"embeddable":true,"href":"https:\/\/zoo.sav.sk\/en\/wp-json\/wp\/v2\/pages\/53"}],"wp:attachment":[{"href":"https:\/\/zoo.sav.sk\/en\/wp-json\/wp\/v2\/media?parent=35"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}